Early detection of infectious disease is crucial for preventing the spread of the infectious agent. In PRRS, current diagnostic methods mainly use the antibody response of individual pigs or herd, which requires at least 7-10 days. Some biological molecules appear in the serum at very early stages of infection and may be useful diagnostically. Our project explored the possibility of identifying such a biomarker for PRRSV infection. We obtained reproducible profiles of low molecular weigh proteins, including one associated with early PRRSV infection, that are present in the serum of pigs. Now we are in the process of fully characterizing the PRRS-associated protein.
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