This proposal evaluated a live attenuated virus vaccine expressing porcine cytokine IL-18 in pigs that is expected to provide enhanced protection against different swine influenza virus (SIV) strains. A killed vaccine with adjuvants and a modified live attenuated virus vaccine…
Evaluation of novel reassortant swine influenza viruses
Since the 2009 pandemic H1N1 virus (pH1N1) was found to transmit to pigs worldwide including in the USA, subsequent reassortment events between pH1N1 and endemic swine influenza viruses (SIVs) have occurred. We have isolated and characterized 60 swine influenza isolates…