Is humoral immunity defective in PCV-2 infected piglets?

Porcine multisystemic wasting syndrome (PMWS) emerged in the mid and late 1990s in herds infected with porcine circovirus type-2 (PCV-2). A growing database of field observations and experimental animal infections considers PCV-2 to be either the cause of PMWS or…

B Cell Repertoire Diversification and Class Switch in PRRS

Successful PRRSV vaccines and vaccination strategies are best employed when the host’s immune response to the pathogen is understood. Since it was generally known that PRRSV caused non-virus specific polyclonal B cell proliferation, we choose to verify and characterize this…

Characterization of the Fetal Immune Response to PRRS

PRRSV causes abnormal development of immune function. This is believed to allow the virus to persist in carrier animals that remain relatively healthy. Such disregulation of the immune is a common feature of many viral infections. Good parasites exist by…