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Federico A. Zuckermann

Nanodisc-based mucosal DIVA vaccine for PRRS virus

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Viral structural components that enable vaccine-induced protective immunity against contemporary high morbidity and high mortality PRRS virus

The production of interferon (IFN)- by an animal in response to a viral infection is known to be a principal determinant of the animal’s ability to fight the infection. In addition, this substance is also known to play a major…

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Immunogenicity and potency of PRRS MLV vaccines with and without interferon-alpha suppressing capacity

Interferon (IFN)-alpha is the most important anti-viral substance produced by mammalian cells in response to a viral infection. Accordingly, the production of IFN-alpha by an animal during a viral infection is known to be a principal determinant of the animal’s…

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A study on the feasibility of using a porcine alveolar macrophage cell line to produce a PRRS modified live virus vaccine

The goals of this project was: 1) to determine the feasibility of using an innovative porcine alveolar macrophage cell line, designated ZMAC-1, for the production of a PRRS modified live virus (MLV) vaccine and 2) to compare the efficacy of…

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Cellular immune response to inactivated PRRS virus vaccines

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Evaluation of nucleic acid delivery methods for a genetic (DNA) vaccine against PRRS

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