The production of interferon (IFN)- by an animal in response to a viral infection is known to be a principal determinant of the animal’s ability to fight the infection. In addition, this substance is also known to play a major…
Immunogenicity and potency of PRRS MLV vaccines with and without interferon-alpha suppressing capacity
Interferon (IFN)-alpha is the most important anti-viral substance produced by mammalian cells in response to a viral infection. Accordingly, the production of IFN-alpha by an animal during a viral infection is known to be a principal determinant of the animal’s…
A study on the feasibility of using a porcine alveolar macrophage cell line to produce a PRRS modified live virus vaccine
The goals of this project was: 1) to determine the feasibility of using an innovative porcine alveolar macrophage cell line, designated ZMAC-1, for the production of a PRRS modified live virus (MLV) vaccine and 2) to compare the efficacy of…