#16-053

Complete

Date Full Report Received

Date Abstract Report Received

Investigation

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Use of antimicrobial feed additives to promote growth and as a ‘security blanket’ has been a valuable tool for efficient swine production for the past six decades. The use of antimicrobials in the feed exerts selection pressure on bacteria to become resistant. The emergence of antimicrobial resistant bacteria (AMR) constitutes a major public health concern. Therefore, in swine production systems, there are considerable interest and effort in identifying feeding and management practices that maintain and improve production efficiency and at the same time do not promote and even reduce the occurrence of AMR in bacteria. The mode of application of antibiotics in food animal production has been considered as one of the main contributing factors for the development and emergence of AMR among gut bacteria. Antibiotics are administered either in-feed, in-water, or parenterally (for disease prevention and treatment). The results obtained from our study contribute to our understanding of the effectiveness of mass versus individual animal antibiotic administration for promoting or mitigating emergence and persistence of AMR among gut and nasal commensal bacteria and foodborne pathogens associated with swine production system. Results from our study will help the swine industry to draw useful conclusions on potential risks for human health caused directly by the use of antibiotic alternative. Our research will significantly advance applied scientific knowledge in ways to manage levels of bacterial resistance in swine production settings that are of concern both to the swine industry and to the public. Results from this study will help to develop on-farm practical intervention strategies to mitigate AMR and toward maintaining the usefulness of current antimicrobial drugs in swine production system.