#06-143

Complete

Date Full Report Received

05/19/2008

Date Abstract Report Received

05/19/2008

Investigation

Institution:
Primary Investigator:

Selection for resistance to PCV2 virus is possible. It can be accomplished by serially scoring pigs for symptoms of PCVAD from 60 to 125 d of age, weighing pigs at these ages, and measuring serum virology at 90 d of age. These traits are heritable, ranging from 17% for PCVAD score to 38% for virology at 90 d of age. Such selection is recommended only in nucleus breeding populations and would be effective only in the presence of PCV2 virus. This quantitative approach to genetic improvement would mimic that that occurs for other traits such as growth rate, food conversion ratio, and carcass leanness. Over time, enhanced resistance to PCV2 in nucleus herds would be transmitted through the breeding pyramid to commercial herds. This quantitative approach would likely be effective, but could be relatively slow as it takes time for small improvements each generation to accumulate into a resistant population and there is lag in the transmission of this improvement from nucleus to commercial herds. Thus, this is a classic example of where genomic selection could enhance rate of response and the effectiveness of marker assisted selection to enhance resistance to pathogens such as PCV2 needs to be evaluated.