Serum Markers of PRRSV Infection

Early detection of infectious disease is crucial for preventing the spread of the infectious agent. In PRRS, current diagnostic methods mainly use the antibody response of individual pigs or herd, which requires at least 7-10 days. Some biological molecules appear…

Direct Physical Characterization of the PRRSV Virion

We have established that PRRSV-infected cells produce only one form (density) of virus and that it accounts for all of the infectivity. The virion is comprised of nucleocapsid at least 5 proteins. Two predicted proteins were not found, and portions…

Implementation of a PRRSV Strain Database

A PRRSV ORF5 database, accessible worldwide, was created for swine producers, practitioners and researchers (http://prrsv.ahc.umn.edu/). This database was established to fulfill one objective of the PRRS Initiative of the National Pork Board. PRRSV ORF5 nucleotide sequence data generated by diagnostic…

Prevention of PRRS by antibody administration

The objectives were to determine if a practical method of producing antibodies to PRRSV could be found which would neutralize all strains of the virus. The naturally occurring ambient strains of PRRSV were inoculated into pigs and induced virus neutralizing…