What is the best oral fluid sampling strategy for PRRSV detection? A spatiotemporal approach.
Characteristics of Unusually Virulent Contemporary PRRSV Isolates
Evaluation, optimization, and application of “processing fluids” for PRRSV monitoring in commercial swine herds
Evaluation, optimization, and application of “processing fluids” for PRRSV monitoring in commercial swine herds
Adaptation of PRRSV to genetic modifications in CD163
Targeted development of neutralizing monoclonal antibodies against PRRSV minor glycoproteins
Development of a live-attenuated PRRSV vaccine capable of eliciting a broad spectrum of heterologous protection
PRRS modified live virus (MLV) vaccines have been licensed for clinical administration for over 20 years. The vaccines confer solid protection against homologous PRRSV strains. However, the extent and duration of protection against heterologous strains is highly variable and mostly…
Epitope Inclusion: Enhancing porcine reproductive and respiratory syndrome virus (PRRSv) vaccine cross-protective efficacy
Producers need better vaccines for controlling disease and spread associated with PRRSv infection. This has been an extremely different task because the face of PRRSv is constantly changing making an escape from the host immune system, which is coupled with…
Mechanism of Antibody-Mediated Neutralization of PRRSV
One of the challenges in developing effective vaccines for PRRSV is the limited understanding of how neutralizing antibody inhibits PRRSV replication, and how variation in PRRSV leads to escape from neutralizing antibody. In this study, we examined how genetic changes…