Introduction of porcine epidemic diarrhea virus (PEDV) into swine herds not only had a significant impact on animal health, but continues to be significant for pork producers and the feed manufacturing industry since it appears to be the first widely…
Evaluation of cross-protective immunity induced by porcine intestinal mesenchymal stromal cell-adapted PEDV
Porcine epidemic diarrhea virus (PEDV) which was isolated in 2013 in the US is causing huge economic losses to Pork Industry. PEDV causes an acute enteric infection in pigs of all ages but infection is severe in suckling piglets causing…
PED virus re-infection rate of sow herds, associated risk factors, production impact and time to achieve stability
The purpose of this study was to quantify the rate of sow herds re-breaking with PED virus and evaluate the impact on performance. The study involved participants’ data from an existing program called the Swine Health Monitoring Project (SHMP). In…
Development of swine influenza virus platform vector vaccines to control swine influenza virus and porcine epidemic diarrhea virus
Influenza A virus (IAV) causes significant losses to the swine industry. Here we constructed a novel attenuated live IAV vaccine designed to elicit an immune response to conserved IAV proteins by removal of the highly variable hemagglutinin gene. A unique…
Infectivity of swine manure from pits on sow farms at varying lengths of time post infection with porcine epidemic diarrhea virus (PEDV)
This project was designed to test manure from manure lagoons on sow farms across the midwest for the presence of viable PEDV in an effort to understand the risk of transmitting this virus during pit pumping. Of the pits we…
PEDv Survivability in Manure-Amended Soil and Evaluation of Lime Application to Soil as a PEDV Biosecurity Measure
This project was conducted in an effort to determine the transmission risk for PEDv in stored manure and manure-amended soil. Specific objectives of this project were to: 1) determine the survivability of the PED virus over time in two common…
Determination of the sites of tissue localization, routes of viral shedding, duration of virus carriage, kinetics of antibody response, and potential of aerosol transmission of Porcine Deltacoronavirus (PDCoV) following inoculation of nursing pigs and their dams
Porcine deltacoronavirus (PDCoV) has recently emerged in the US. The purpose of this investigation was to determine the sites of tissue localization, routes of viral shedding, duration of virus carriage, kinetics of antibody response, and potential of aerosol transmission of…
Environmental stability of PEDV (porcine epidemic diarrhea virus)
An evaluation of a shipping model to investigate PEDV introduction into the USA
This study describes a model developed to evaluate the transboundary risk of PEDV-contaminated swine feed ingredients and the effect of two mitigation strategies during a simulated transport event from China to the US. Ingredients imported to the USA from China…
Extent of contamination, quantification and survival of PEDV in fomites and effect of disinfectants on swine coronaviruses
This study was designed to assess the survivability of porcine epidemic diarrhea virus (PEDV) in fomites and determine the efficacy of four commonly used disinfectants against the three swine enteric coronaviruses; porcine epidemic diarrhea virus (PEDV), porcine delta coronavirus (PDCoV)…