CategorySwine Health - General Disease
Date Full Report Received07/01/2011
Date Abstract Report Received07/01/2011
InvestigationInstitution: The Ohio State University Research Foundation (OSURF)
Primary Investigator: Steven Krakowka
Funded ByNational Pork Board
2. There are two reasons (academic and practical) that the data generated by this NPB grant are important to producers and the swine industry:
Firstly, a successful outcome (i.e. archival PCV2 recovered from swine tissues 25-years prior to the first reported cases of postweaning multi-systemic wasting syndrome is avirulent for pigs) provides a credible explanation for the historical presence of avirulent PCV2 in swine and also provides a molecular explanation for the sudden emergence of the porcine circovirus diseases (PCVDs) in global swine populations.
Secondly, development of an avirulent yet immunogenic and genomically stable PCV2 (i. e. archival PCV2) will provide the industry with a potential candidate modified-live PCV2 for protection of swine against the PCVDs.