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SPECIAL REQUEST FOR PROPOSALS

SWINE HEALTH – PMWS

Research Proposal Information for SUMMER 2006 Funding

Introduction

It has not been unusual for clinical PMWS to be diagnosed on farms in the U.S. based on the case definition published by Sorden.  (Sorden, S.D., 2000.  Update on porcine circovirus and post-weaning multisystemic wasting syndrome (PMWS).  Swine Health Prod. 8, 133-136.)  These affected farms have historically been positive for Porcine Circovirus type 2 (PCV2).

However, an increase in the incidence of the severe form has been reported in the U.S. since the fall of 2005.  Clinical signs of the more severe form of PMWS include anorexia, rapid weight loss, enlarged lymph nodes, and respiratory signs. Theories for etiology of this increase include the emergence of a completely new infectious agent; development of a new, more virulent and/or transmissible strain of PCV2; or the emergence of infectious or non-infectious disease co-factors that interact with PCV2 to increase the incidence of clinical PCV2 associated disease.

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