Evaluation of an accelerated hydrogen peroxide disinfectant to inactivate porcine epidemic diarrhea virus in swine feces on metal surfaces under freezing conditions

Iowa State University; Holtkamp


Objectives of the Research Project:

The objective of this study is to test the same accelerated hydrogen peroxide disinfectant mixed with propylene glycol (PG) under freezing conditions (-10˚C) for inactivating PEDV in the presence of feces on metal surfaces found in livestock trailers.


Understanding the actions and implications of people during unloading at lairage on PEDV contamination of swine transportation equipment.

University of Illinois; Lowe


Objectives of Research Project:

  1. Estimate the number and nature of contacts between lairage and swine transportation equipment across the US industry.
  2. Quantify the risk of a lairage-truck contact under various environmental conditions and concentration levels for the spread of PEDV.
  3. Estimate the level of contamination with PEDV at multiple locations within US packing plants where lairage-truck contact occurs.
  4. Develop a set of recommended best management practices for each season based on risk modeling that will be validated in future studies.


Pathogenesis of the S INDEL PEDV in nursing piglets and cross-protection against the US original highly virulent PEDV strains

The Ohio State University; Wang


Objectives of Research Project:

  1. To study the pathogenesis of S INDEL PEDV Iowa106 strain in nursing piglets and cross-protection to the highly virulent PEDV PC21A strain.


Extent of contamination, quantification and survival of PEDV in fomites and effect of disinfectants on swine coronaviruses

University of Minnesota; Torremorell


Objectives of Research Project:

  • Evaluate the extent of contamination, quantity and survivability of PEDV on porous and non-porous fomites
  • Evaluate the comparative effect of disinfectants against PEDV, TGEV, PoDCV


Miscellaneous studies on PEDV survival

University of Minnesota; Goyal


Objectives of Research Project:

  1. Inactivation kinetics of the above three viruses with different concentrations of lime.
  2. Survival of the three viruses in gelatin-coated vitamins and other feed ingredients.
  3. The effect of pH on inactivation of the three viruses.


Evaluation of cross-protective immunity induced by porcine intestinal mesenchymal stromal cell-adapted PEDV

The Ohio State University; Khatri    


Objectives of Research Project:

Overall objective is to examine if porcine duodenal mesenchymal stromal cells (D-MSCs)-adapted porcine epidemic diarrhea virus (PEDV) induces cross-protection against virulent and variant PEDV.

  • To examine the pathogenesis of MSC-adapted PEDV in pigs.


PEDV Survivability in Manure-Amended Soil and Evaluation of Lime Application to Soil as a PEDV Biosecurity Measure

University of Nebraska-Lincoln; Schmidt


Objectives of Research Project:

  1. Determine survivability of PEDv over time in two common soils treated with PEDv-positive swine slurry at two moisture regimes and in three climates.
  2. Determine impact of fall field lime application on PEDv survivability in soil


Infectivity of swine manure from pits on sow farms at varying lengths of time post infection with porcine epidemic diarrhea virus (PEDV)

Swine Vet Center; Tousignant


Objectives of Research Project:

  • Determine if sow farms using white wash are less likely to have viable PEDV across different areas of the barn, including:

-Gilt development, gestation, and farrowing (primary interest).

  • Identify characteristics of the manure in each location on individual farms that favor the presence of dead (or live) PEDV.

-Attempt to identify associations between whitewash use and increased manure pH.


PEDV infection risk factor analysis

Swine Vet Center; Tousignant


  1. Gather information regarding biosecurity measures and other risk factors (ie PADRAP) from the approximately 190 sow farms and boar studs within the Swine Vet Center practice.
  2. Quantify the effect of those factors on those farms to prevent PEDV infection through the use of case control studies and proportional hazards regression modeling.
  3. Quantify the effect of various control measures on PEDV positive sow farms on time to negative pig production and base line production.


PED virus re-infection rate of swine herds, associated risk factors, production impact and time to achieve stability

University of Minnesota; Morrison


Objectives of Research Project:

Objective 1. Determine the reinfection rate of PEDv.

Objective 2. Identify risk factors associated with reinfection of PEDv.

Objective 3. Evaluate production impact and management strategies for stability.